Herb-drug interactions | An-Najah Staff

Antibacterial Activity of Rosmarinus Officinalis L. Alone and In Combination with Cefuroxime against Methicillin–Resistant Staphylococcus Aureus

Mon, 2014-03-03 10:14 — Kamel Mohammed Dauod Adwan

Journal Title, Volume, Page:

Asian Pacific Journal of Tropical Medicine Volume 3, Issue 2, February 2010, Pages 121–123

Year of Publication:

2010

Link:

http://www.sciencedirect.com/science/article/pii/S1995764510600491

Authors:

Naser Jarrar

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

Awni Abu-Hijleh

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

Kamel Adwan

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

Preferred Abstract (Original):

Objective To determine the antimicrobial activity of rosemary (Rosmarinus officinalis L.) and to investigate the synergistic effects of this extract combined with ceforuxime against methicillin-resistant Staphylococcus aureus (MRSA).
Methods The inhibitory and bactericidal activities of rosemary ethanol extract, alone and in combination with cefuroxime, were studied.
Results The minimum inhibitory concentrations (MICs) of the ethanol extract of rosemary were in the range of 0.39–3.13 mg/mL. The minimum bactericidal concentrations (MBCs) were usually equal to or double that MICs. The antimicrobial activity of combinations of the ethanol extract of rosemary and cefuroxime indicated their synergistic effects against all MRSAs.
Conclusions The present work clearly demonstrates that rosemary has a key role in the elevation of susceptibility to β-lactams.

Antibacterial activity of Rosmarinus officinalis L. alone and in combination with cefuroxime against methicillin-resistant Staphylococcus aureus

Sun, 2013-04-14 16:10 — Awni A. M. Abu-Hijleh

Journal Title, Volume, Page:

Asian Pacific Journal of Tropical Medicine Volume 3, Issue 2, February 2010, Pages 121–123

Year of Publication:

2010

Link:

http://www.sciencedirect.com/science/article/pii/S1995764510600491

Authors:

Naser Jarrar

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Awni Abu-Hijleh

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine

[email protected]

Kamel Adwan

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Objective To determine the antimicrobial activity of rosemary (Rosmarinus officinalis L.) and to investigate the synergistic effects of this extract combined with ceforuxime against methicillin-resistant Staphylococcus aureus (MRSA).
Methods The inhibitory and bactericidal activities of rosemary ethanol extract, alone and in combination with cefuroxime, were studied.
Results The minimum inhibitory concentrations (MICs) of the ethanol extract of rosemary were in the range of 0.39–3.13 mg/mL. The minimum bactericidal concentrations (MBCs) were usually equal to or double that MICs. The antimicrobial activity of combinations of the ethanol extract of rosemary and cefuroxime indicated their synergistic effects against all MRSAs.
Conclusions The present work clearly demonstrates that rosemary has a key role in the elevation of susceptibility to β-lactams.

Antibacterial Activity of Common Varthemia, Varthemia Iphionoides Ethanol Extract Alone And In Combination With Cefotaxime

Sun, 2013-04-14 15:51 — Awni A. M. Abu-Hijleh

Journal Title, Volume, Page:

Advances in Biological Research 3 (5-6): 144-147

Year of Publication:

2009

Link:

http://www.idosi.org/abr/abr3%285-6%29.htm

Authors:

Awni Abu-Hijleh

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine

[email protected]

Naser Jarrar

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Kamel Adwan

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

To assess the clinical utility of the crude ethanolic extract of the leaves of Varthemia iphionoides (Compositae), minimal inhibitory concentrations (MICs) were determined using agar dilution technique. Accordingly, The MICs of of this plant extract ranged from 0.0313-1 mg/ml for three clinical taphylacaccus aureus strains and ATCC strains of Bacillus subtilis and Staphylococcus epidermidis, whereas Escherichia coli studied in this report was found to exhibit higher MIC value (4 mg/ml). The effect of combinations of ethanolic extract of Varthemia iphionoides and cefotaxime was investigated by means of fractional inhibitory concentration (FIC) indices. Using the FIC indices, synergistic interactions were observed against B. subtilis (ATCC 6633) and S. ureus strains (FIC indices of 0.75-0.875); while combinations against E. coli and S. epidermidis (ATCC 25923) exhibited antagonistic interactions (FIC indices of 2.5 to 16.4). Synergy was confirmed at cefotaxime concentrations corresponding to 1/2 MIC and an ethanol extract concentrations corresponding to 1/4 MIC and lower.

Antibacterial Activity of Common Varthemia, Varthemia Iphionoitks Ethanol Extract Alone and in Combination with Cefotaxime

Mon, 2013-03-04 13:05 — Kamel Mohammed Dauod Adwan

Journal Title, Volume, Page:

Advances in Biological Research 3 (5-6): 144-147, 2009

Year of Publication:

2009

Link:

http://www.idosi.org/abr/3%285-6%29/1.pdf

Authors:

Awni Abu-Hijleh

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Naser Jarrar

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Kamel Adwan

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine

[email protected]

Preferred Abstract (Original):

To assess the clinical utility of the crude ethanolic extract of the leaves of Varthemia iphionoides (Compositae), minimal inhibitory concentrations eJ'v1Ies) were determined using agar dilution technique. Accordingly, The MICs of of this plant extract ranged from 0.0313-1 mg/ml for three clinical Staphylacaccus aureus strains and ATCC strains of Bacillus subtilis and Staphylococcus epidermidis, whereas Escherichia coli studied in this report was fOlUld to exhibit higher 1v1Ie value (4 mg/ml). The effect of combinations of ethanolic extract of Varthemia iphionoides a0nd cefotaxime was investigated by means of fractional inhibitory concentration (FIe) indices. Using the FIe indices, synergistic interactions were observed against B. subtilis (ATCC 6633) and S. aureus strains (FIC indices of 0.75-0.875); while combinations against E. cali and S. epidermidis (ATCC 25923) exhibited antagonistic interactions (FIC indices of 2.5 to 16.4). Synergy was confirmed at cefotaxime concentrations corresponding to 1/2 MIC and an ethanol extract concentrations corresponding to 1/41v1IC and lower.

Antibacterial Activity of Common Varthemia, Varthemia iphionoitks Ethanol Extract Alone and in Combination with Cefotaxime

Fri, 2013-03-01 11:22 — Naser Rushdi Mahmoud Jarrar

Journal Title, Volume, Page:

Advances in Biological Research 3 (5-6): 144-147, 2009

Year of Publication:

2009

Link:

http://www.idosi.org/abr/abr3%285-6%29.htm

Authors:

Awni Abu-Hijleh

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Naser Jarrar

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine

[email protected]

Kamel Adwan

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

To assess the clinical utility of the crude ethanolic extract of the leaves of Varthemia iphionoides (Compositae), minimal inhibitory concentrations eJ'v1Ies) were determined using agar dilution technique. Accordingly, The MICs of of this plant extract ranged from 0.0313-1 mg/ml for three clinical Staphylacaccus aureus strains and ATCC strains of Bacillus subtilis and Staphylococcus epidermidis, whereas Escherichia coli studied in this report was fOlUld to exhibit higher 1v1Ie value (4 mg/ml). The effect of combinations of ethanolic extract of Varthemia iphionoides and cefotaxime was investigated by means of fractional inhibitory concentration (FIe) indices. Using the FIe indices, synergistic interactions were observed against B. subtilis (ATCC 6633) and S. aureus strains (FIC indices of 0.75-0.875); while combinations against E. cali and S. epidermidis (ATCC 25923) exhibited antagonistic interactions (FIC indices of 2.5 to 16.4). Synergy was confirmed at cefotaxime concentrations corresponding to 1/2 MIC and an ethanol extract concentrations corresponding to 1/41v1IC and lower. Key words: Varthemia iphionoides . Medicinal plants . Antibacterial activity . Herb-drug interactions . Plant extracts

Antibacterial Activity of Rosmarinus Officinalis L. Alone And In Combination With Cefuroxime Against Methicillin-Resistant Staphylococcus Aureus

Tue, 2011-03-08 14:04 — Kamel Mohammed Dauod Adwan

Journal Title, Volume, Page:

Asian Pacific Journal of Tropical Medicine Volume 3, Issue 2, February 2010, Pages 121-123

Year of Publication:

2010

Link:

http://linkinghub.elsevier.com/retrieve/pii/S1995764510600491

Authors:

Naser Jarrar

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Awni Abu-Hijleh

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Kamel Adwan

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine

[email protected]

Preferred Abstract (Original):

Objective To determine the antimicrobial activity of rosemary (Rosmarinus officinalis L.) and to investigate the synergistic effects of this extract combined with ceforuxime against methicillin-resistant Staphylococcus aureus (MRSA).
Methods The inhibitory and bactericidal activities of rosemary ethanol extract, alone and in combination with cefuroxime, were studied.
Results The minimum inhibitory concentrations (MICs) of the ethanol extract of rosemary were in the range of 0.39–3.13 mg/mL. The minimum bactericidal concentrations (MBCs) were usually equal to or double that MICs. The antimicrobial activity of combinations of the ethanol extract of rosemary and cefuroxime indicated their synergistic effects against all MRSAs.
Conclusions The present work clearly demonstrates that rosemary has a key role in the elevation of susceptibility to β-lactams.

Antibacterial Activity of Rosmarinus Officinalis L. Alone And In Combination With Cefuroxime Against Methicillin-Resistant Staphylococcus Aureus

Tue, 2011-03-08 14:03 — Naser Rushdi Mahmoud Jarrar

Journal Title, Volume, Page:

Asian Pacific Journal of Tropical Medicine Volume 3, Issue 2, February 2010, Pages 121-123

Year of Publication:

2010

Link:

http://linkinghub.elsevier.com/retrieve/pii/S1995764510600491

Authors:

Naser Rushdi Mahmoud Jarrar

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine

[email protected]

Awni Abu-Hijleh

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Kamel Adwan

Department of Biology and Biotechnology, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Objective: To determine the antimicrobial activity of rosemary (Rosmarinus officinalis L.) and to investigate the synergistic effects of this extract combined with ceforuxime against methicillin-resistant Staphylococcus aureus (MRSA).
Methods:The inhibitory and bactericidal activities of rosemary ethanol extract, alone and in combination with cefuroxime, were studied.
Results : The minimum inhibitory concentrations (MICs) of the ethanol extract of rosemary were in the range of 0.39–3.13 mg/mL. The minimum bactericidal concentrations (MBCs) were usually equal to or double that MICs. The antimicrobial activity of combinations of the ethanol extract of rosemary and cefuroxime indicated their synergistic effects against all MRSAs.
Conclusions: The present work clearly demonstrates that rosemary has a key role in the elevation of susceptibility to β-lactams.