An-Najah Staff

Ethanolic extracts of six plants: Arum palaestinum Bioss, Urtica pilulifera L., Thymbra capitata (L.) Cav., Origanum syriacum L., Teucrium creticum L., and Teucrium polium L., used in Traditional Arabic Palestinian Herbal Medicine were evaluated for their antibacterial, anti-candida, and antidermatophyte activities using well diffusion, micro-dilution and food poisoned techniques. The extracts were tested against: six bacterial strains including Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi, Escherichia coli and Klebsiella pneumoniae; five Candida albicans isolates, and two dermatophytes: Microsporum canis, and Trichophyton rubrum. The most active plants extracts were T. capitata and O. syriacum against the tested bacteria, while the remaining plant extracts did not express any activity or exhibited only very low activity against tested bacteria species and candida isolates. O. syriacum was also the most active plant against all Candida strains with inhibition zones that ranged from 22.5 to 29.5 mm. On the other hand, T. capitata extract showed the highest activity against the test dermatophytes (producing a complete inhibition at = 45 µg/mL).

Ethanolic extracts of six plants: Arum palaestinum Bioss, Urtica pilulifera L., Thymbra capitata (L.) Cav., Origanum syriacum L., Teucrium creticum L., and Teucrium polium L., used in Traditional Arabic Palestinian Herbal Medicine were evaluated for their antibacterial, anti-candida, and antidermatophyte activities using well diffusion, micro-dilution and food poisoned techniques. The extracts were tested against: six bacterial strains including Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi, Escherichia coli and Klebsiella pneumoniae; five Candida albicans isolates, and two dermatophytes: Microsporum canis, and Trichophyton rubrum. The most active plants extracts were T. capitata and O. syriacum against the tested bacteria, while the remaining plant extracts did not express any activity or exhibited only very low activity against tested bacteria species and candida isolates. O. syriacum was also the most active plant against all Candida strains with inhibition zones that ranged from 22.5 to 29.5 mm. On the other hand, T. capitata extract showed the highest activity against the test dermatophytes (producing a complete inhibition at = 45 µg/mL). 

Ethanolic extract of dried Rumex cyprius Murb (polygonaceae) was tested against four pathogenic fungi: three dermatophytes, Microsporum canis, Trichophyton mentagrophytes and T. rubrum, and the causative agent of chalkbrood disease of bees, Ascophaera apis. The extract showed considerable activity against all these fungi. One of the main constituents of Rumex cyprius was isolated and tested for its antimycotic activity. It showed a significant activity against the test fungi and was identified as 1,3,8-trihydroxy-6-methylanthracene-9,10-dione based on its IR, UV-V and ¹H NMR spectra.

Ethanolic extract of dried Rumex cyprius Murb (polygonaceae) was tested against four pathogenic fungi: three dermatophytes, Microsporum canis, Trichophyton mentagrophytes and T. rubrum, and the causative agent of chalkbrood disease of bees, Ascophaera apis. The extract showed considerable activity against all these fungi. One of the main constituents of Rumex cyprius was isolated and tested for its antimycotic activity. It showed a significant activity against the test fungi and was identified as 1,3,8-trihydroxy-6-methylanthracene-9,10-dione based on its IR, UV-V and ¹H NMR spectra. 

The potential of antifungal effects of Walnut (Juglans regia L., Juglandaceae) ethanolic and chloroform extracts was reported against four pathogenic fungi: three dermatophytes, Microsporum canis (MC), Trichophyton mentagrophytes (TM) and T. Rubrum (TR), and the causative agent of chalk brood disease of bees, Ascophaera apis (AsA). Both extracts had considerable activity against the studied fungi. The main antifungal component of walnut was isolated and tested for its antimycotic activity individually. Based on its IR, 13C and 1H NMR analysis the main significant activity against was indentifying to be 5-hydroxy- 1, 4-naphthoquinone (Juglone).

Ethanolic extract of dried Rumex cyprius Murb (polygonaceae) was tested against four pathogenic fungi: three dermatophytes, Microsporum canis, Trichophyton mentagrophytes and T. rubrum, and the causative agent of chalkbrood disease of bees, Ascophaera apis. The extract showed considerable activity against all these fungi. One of the main constituents of Rumex cyprius was isolated and tested for its antimycotic activity. It showed a significant activity against the test fungi and was identified as 1,3,8-trihydroxy-6-methylanthracene-9,10-dione based on its IR, UV-V and ¹H NMR spectra.

The potential of antifungal effects of Walnut (Juglans regia L., Juglandaceae) ethanolic and chloroform extracts was reported against four pathogenic fungi: three dermatophytes, Microsporum canis (MC), Trichophyton mentagrophytes (TM) and T. Rubrum (TR), and the causative agent of chalk brood disease of bees, Ascophaera apis (AsA). Both extracts had considerable activity against the studied fungi. The main antifungal component of walnut was isolated and tested for its antimycotic activity individually. Based on its IR, 13C and 1H NMR analysis the main significant activity against was indentifying to be 5-hydroxy- 1, 4-naphthoquinone (Juglone).

The potential of antifungal effects of Walnut (Juglans regia L., Juglandaceae) ethanolic and chloroform extracts was reported against four pathogenic fungi: three dermatophytes, Microsporum canis (MC), Trichophyton mentagrophytes (TM) and T. Rubrum (TR), and the causative agent of chalk brood disease of bees, Ascophaera apis (AsA). Both extracts had considerable activity against the studied fungi. The main antifungal component of walnut was isolated and tested for its antimycotic activity individually. Based on its IR, 13C and 1H NMR analysis the main significant activity against was indentifying to be 5-hydroxy- 1, 4-naphthoquinone (Juglone).

The aqueous extracts (15 micrograms ml-1 medium) of 22 plants used in folkloric medicine in Palestine were investigated for their antifungal activity and minimum inhibitory concentrations (MICs) against nine isolates of Microsporum canis, Trichophyton mentagrophytes and Trichophyton violaceum. The extract of the different plant species reduced colony growth of the three dermatophytes by 36 to 100% compared with the control treatment. Antimycotic activity of the extract against the three dermatophytes varied significantly (P < 0.05) between test plants. Extracts of Capparis spinosa and Juglans regia completely prevented growth of M. canis and T. violaceum. The most active extracts (90-100% inhibition) were those of Anagallis arvensis, C. spinosa, J. regia, Pistacia lentiscus and Ruta chalapensis against M. canis; Inula viscosa, J. regia and P. lentiscus against T. mentagrophytes; and Asphodelus luteus, A. arvensis, C. spinosa, Clematis cirrhosa, I. viscosa, J. regia, P. lentiscus, Plumbago europea, Ruscus aculeatus, Retema raetam and Salvia fruticosa against T. violaceum. The MICs of these most active plants ranged from 0.6 to 40 micrograms ml-1. The three dermatophytes differed significantly with regard to their susceptibility to plant extracts. Trichophyton violaceum was the most susceptible being completely inhibited by 50% of the extracts followed by M. canis and T. mentagrophytes which were completely inhibited by only 23 and 14% of the extracts, respectively.