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Isolation and Antifungal Evaluation of Juglans Regia L Extracts

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Fri, 2013-03-01 22:58 — Nidal Zatar
Journal Title, Volume, Page: 
IJRRAS, 13(2) (2012) 655-660
Year of Publication: 
2012
Link: 
http://www.arpapress.com/Volumes/Vol13Issue2/IJRRAS_13_2_34.pdf
Authors: 
Nidal A. Zatar
Department of Chemistry, Faculty of Science, An - Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Chemistry, Faculty of Science, An - Najah National University, Nablus, Palestine
[email protected]
Ahmad I. Husein
Department of Chemistry, Faculty of Science, An - Najah National University, Nablus, Palestine
Mohammed A. Al - Nuri
Department of Chemistry, Faculty of Science, An - Najah National University, Nablus, Palestine
Waheed Jondi
Department of Chemistry, Faculty of Science, An - Najah National University, Nablus, Palestine
Mohammed S. Ali-Shtayeh
Biodiversity & Environmental Research Center (BERC), Til, Nablus, POB 696, Palestine, West Bank (The Palestinian Authority)
Ismail Warad
Department of Chemistry, Faculty of Science, An - Najah National University, Nablus, Palestine
Preferred Abstract (Original): 

The potential of antifungal effects of Walnut (Juglans regia L., Juglandaceae) ethanolic and chloroform extracts was reported against four pathogenic fungi: three dermatophytes, Microsporum canis (MC), Trichophyton mentagrophytes (TM) and T. Rubrum (TR), and the causative agent of chalk brood disease of bees, Ascophaera apis (AsA). Both extracts had considerable activity against the studied fungi. The main antifungal component of walnut was isolated and tested for its antimycotic activity individually. Based on its IR, 13C and 1H NMR analysis the main significant activity against was indentifying to be 5-hydroxy- 1, 4-naphthoquinone (Juglone).

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