Isolation And Antifungal Evaluation of Juglans Regia L Extracts

Journal Title, Volume, Page:

International Journal of Research and Reviews in Applied Sciences, 13 (2),November 2012, 655

Year of Publication:

2012

Link:

http://www.arpapress.com/ijrras/Volume13Issue2.aspx

Authors:

Ahmad I. Husein

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

Mohammed A. Al-Nuri

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Nidal A. Zatar

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Waheed Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Mohammed S. Ali-Shtayeh

Biodiversity & Environmental Research Center (BERC), Til, Nablus, POB 696, Palestine, West Bank (The Palestinian Authority)

Ismail Warad

Department of Chemistry, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia

Current Affiliation:

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

Preferred Abstract (Original):

The potential of antifungal effects of Walnut (Juglans regia L., Juglandaceae) ethanolic and chloroform extracts was reported against four pathogenic fungi: three dermatophytes, Microsporum canis (MC), Trichophyton mentagrophytes (TM) and T. Rubrum (TR), and the causative agent of chalk brood disease of bees, Ascophaera apis (AsA). Both extracts had considerable activity against the studied fungi. The main antifungal component of walnut was isolated and tested for its antimycotic activity individually. Based on its IR, 13C and 1H NMR analysis the main significant activity against was indentifying to be 5-hydroxy- 1, 4-naphthoquinone (Juglone).

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Isolation And Antifungal Evaluation of Juglans Regia L Extracts