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Roemeria hybrida

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Phytoconstituents, Free Radical Scavenging Potential, Total Phenols and Total Flavonoids Assessments for Violet Horned Poppy from Jerusalem Mountains

Mon, 2016-02-01 11:53 — Nidal Amin Jaradat
Journal Title, Volume, Page: 
J. Mater. Environ. Sci. 6 (10) (2015) 2958-2966 ISSN : 2028-2508 CODEN: JMESCN
Year of Publication: 
2015
Authors: 
Nidal Amin Jaradat
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
[email protected]
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Fatima Mohammed Hussen
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Anas Al Ali
Department of Chemistry, Faculty of Science, An-Najah National University, P.O. Box 7, Nablus, Palestine
Hasan Y. Alniss
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Maram Dweikat
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Preferred Abstract (Original): 
Most of the world population especially in the developing countries used herbal medicaments due to their cultural acceptability, safety, efficacy and fewer side effects for their primary health care. Dearth in the studies related to Roemeria hybrida has prompted us to do the present work. This study was designed to detect the presence of bioactive compounds and to evaluate total phenols, total flavonoids contents and antioxidant activity of Roemeria hybrida plant growing in the mountains of Jerusalem/ Palestine. The results of such a study would be important to prove or disprove its utilization in the Palestinian folk medicine for treatment of retinopathy (diabetes mellitus) and other diseases. Total flavonoid contents were determined by using Rutin reference standard method and total phenols determined by using Folin Ciocalteu’s method while antioxidant activity evaluated by using 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay. The results showed that the aqueous extract contains carbohydrate, reducing sugars, glycosides, flavonoids, terpenoids, phenols and tannin. The result also revealed that this plant has an antioxidant activity (IC50=31.405±0.21µg/ml), as well as total phenol was 30.448±0.56 mg of GA/g while the total flavonoid was 53.821 ±0.42 mg rutin/g of the plant extract. Therefore R. hybrida can be a good candidate for manufacturing of pharmacological active pharmaceuticals, cosmeceuticals and nutraceutical formulations.
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