antibiotic-resistance

nsabuhasan's picture

Molecular Epidemiology of Antibiotic-Resistant Escherichia Coli Isolated From Hospitalized Patients with Urinary Tract Infections in Northern Palestine

Journal Title, Volume, Page: 
Pol J Microbiol.;53(1):23-6 Year of Publication: 2004
Year of Publication: 
2004
Authors: 
Abu-Shanab B
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Adwan K
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Abu-Hasan N
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Adwan G
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Jarrar N.
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Preferred Abstract (Original): 
Eighty isolates of Escherichia coli were collected in Northern Palestine throughout the 1996 to 2000 period from hospitalized patients with urinary tract infections (UTIs). Resistance rates were ampicillin, 65%; co-trimoxazole, 55%; cefuroxime, 10%; cefotaxime, 7.5%; ceftazidime, 2.5%; ciprofloxacin, 12.5%; gentamicin, 6.25% and amikacin, 1.25%. No imipenem-resistant isolates were identified. To determine whether this was due to intra-hospital transmission of resistant strains, clonal structure of 10 multiple-resistant isolates was examined by genomic DNA fingerprinting by enterobacterial repetitive intergenic concensus-polymerase chain reaction (ERIC-PCR) and all were clonally distinct. Thus, these strains are likely resistant due to convergent acquisition of resistance determinants by genetically unrelated uropathogenic strains rather than epidemic spread of resistant isolates.
adwank's picture

Molecular Epidemiology of Antibiotic-Resistant Escherichia coli Isolated from Hospitalized Patients with Urinary Tract Infections in Northern Palestine

Journal Title, Volume, Page: 
Polish Journal of Microbiology 2004, Vol. 53, No 1, 23-26
Year of Publication: 
2004
Authors: 
Adwan K.
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Current Affiliation: 
Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine
Abu-Hasan N.
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Adwan G
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Jarrar N
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Abu-Shanab B
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Al-Masri M
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Preferred Abstract (Original): 

Eighty isolates of Escherichia coli were collected in Northern Palestine throughout the 1996 to 2000 period from hospitalized patients with urinary tract infections (UTIs). Resistance rates were ampicillin, 65%; co-trimoxazole, 55%; cefuroxime, 10%; cefotaxime, 7.5%; ceftazidime, 2.5%; ciprofloxacin, 12.5%; gentamicin, 6.25% and amikacin, 1.25%. No imipenem-resistant isolates were identified. To determine whether this was due to intra-hospital transmission of resistant strains, clonal structure of 10 multiple-resistant isolates was examined by genomic DNA fingerprinting by enterobacterial repetitive intergenic concensus-polymerase chain reaction (ERIC-PCR) and all were clonally distinct. Thus, these strains are likely resistant due to convergent acquisition of resistance determinants by genetically unrelated uropathogenic strains rather than epidemic spread of resistant isolates.

Naser Jarrar's picture

Molecular Epidemiology of Antibiotic-Resistant Escherichia coli Isolated from Hospitalized Patients with Urinary Tract Infections in Northern Palestine

Journal Title, Volume, Page: 
Polish Journal of Microbiology 2004, Vol. 53, No 1, 23-26
Year of Publication: 
2004
Authors: 
K. ADWAN
Department of Biological Sciences, An-Najah National University, Nablus, P. O. Box 7, Palestine
N. ABU-HASAN
Department of Biological Sciences, An-Najah National University, Nablus, P. O. Box 7, Palestine
G. ADWAN
Department of Biological Sciences, An-Najah National University, Nablus, P. O. Box 7, Palestine
N. JARRAR
Department of Biological Sciences, An-Najah National University, Nablus, P. O. Box 7, Palestine
Current Affiliation: 
Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine
B. ABU-SHANAB
Department of Biological Sciences, An-Najah National University, Nablus, P. O. Box 7, Palestine
M. AL-MASRI
Department of Biological Sciences, An-Najah National University, Nablus, P. O. Box 7, Palestine
Preferred Abstract (Original): 
Abstract Eighty isolates of Escherichia coli were collected in Northern Palestine throughout the 1996 to 2000 period from hospitalized patients with urinary tract infections (UTIs). Resistance rates were ampicillin, 65%; co-trimoxazole, 55%; cefuroxime, 10%; cefotaxime, 7.5%; ceftazidime, 2.5%; ciprofloxacin, 12.5%; gentamicin, 6.25% and amikacin, 1.25%. No imipenem-resistant isolates were identified. To determine whether this was due to intra-hospital transmission of resistant strains, clonal structure of 10 multiple-resistant isolates was examined by genomic DNA fingerprinting by enterobacterial repetitive intergenic concensus-polymerase chain reaction (ERICPCR) and all were clonally distinct. Thus, these strains are likely resistant due to convergent acquisition of resistance determinants by genetically unrelated uropathogenic strains rather than epidemic spread of resistant isolates. Key words: E. coli, antibiotic-resistance, DNA fingerprinting, ERIC-PCR * Correspondence to: Dr. K. Adwan, Department of Biological Sciences, An-Najah N. University, P. O. Box (7)-Nablus, Palestine. Fax: 972 9 387 982; e-mail: adwank@yahoo.com
bassamas's picture

Molecular Epidemiology of Antibiotic-Resistant Escherichia Coli Isolated From Hospitalized Patients with Urinary Tract Infections in Northern Palestine

Journal Title, Volume, Page: 
Pol J Microbiol.;53(1):23-6
Year of Publication: 
2004
Authors: 
Abu-Shanab B
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Current Affiliation: 
Department of Animal Production and Health, Faculty of Agriculture and Veterinary Medicine, An Najah National University, Nablus, Palestine
Adwan K
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Abu-Hasan N
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Adwan G
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Jarrar N
Department of Biological Sciences, An-Najah N University, Nablus, Palestine
Al-Masri M
Preferred Abstract (Original): 
Eighty isolates of Escherichia coli were collected in Northern Palestine throughout the 1996 to 2000 period from hospitalized patients with urinary tract infections (UTIs). Resistance rates were ampicillin, 65%; co-trimoxazole, 55%; cefuroxime, 10%; cefotaxime, 7.5%; ceftazidime, 2.5%; ciprofloxacin, 12.5%; gentamicin, 6.25% and amikacin, 1.25%. No imipenem-resistant isolates were identified. To determine whether this was due to intra-hospital transmission of resistant strains, clonal structure of 10 multiple-resistant isolates was examined by genomic DNA fingerprinting by enterobacterial repetitive intergenic concensus-polymerase chain reaction (ERIC-PCR) and all were clonally distinct. Thus, these strains are likely resistant due to convergent acquisition of resistance determinants by genetically unrelated uropathogenic strains rather than epidemic spread of resistant isolates.
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