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Oxidation of some Alicyclic Amines by Potassium Hexacyanoferrate (III) in Alkaline Medium: A Kinetic and Mechanistic Study

Sun, 2014-12-28 11:07 — Mohammed Al-Subu'

Journal Title, Volume, Page:

An-Najah University Journal for Research - Natural Sciences - Volume 15, Issue 1, 2001

Year of Publication:

2001

Link:

http://scholar.najah.edu/publication/journal-article/oxidation-some-alicyclic-am...

Authors:

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hanoun

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

M.J. Musmar

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Oxidation of some alicyclic amines (morpholine, piperazine and piperidine) by potassium hexacyanoferrate(III) in basic medium has been investigated at 35°C. Stoichiometric results showed that four moles of hexacyanoferrate(III) were consumed per mole of piperidine or morpholine whereas piperazine consumed eight moles of the oxidant to produce the corresponding lactams. Kinetic studies indicated that piperidine and morpholine also followed different kinetics from that of piperazine, being first order in the amine concentration and independent of the concentrations of hexacyanoferrate(???) and hydroxide ion, while in the case of piperazine, the reaction was first order in both oxidant and substrate concentrations and zero order with respect to the concentration of hydroxide ion. The changes in reaction rate due to changing ionic strength of the medium as well as other factors has also been investigated. The activation parameters of the oxidation process have been evaluated and a mechanism consistent with the observed kinetics has been proposed. Keywords: Hexacyanoferrate(III), morpholine, piperazine, piperidine, oxidation, lactam.

Osmium(VIII)-Catalyzed Oxidation of Some Cyclic Amines by Potassium Hexacyanoferrate(III) in Alkaline Media: a Kinetics and Mechanistic Study

Wed, 2014-04-02 12:27 — Dr. Waheed J. Jondi

Journal Title, Volume, Page:

Chemistry of Heterocyclic Compounds, Volume 39, Issue 4, pp 478-484

Year of Publication:

2003

Link:

http://link.springer.com/article/10.1023%2FA%3A1024765330259

Authors:

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hannoun

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. J. Musmar

College of Pharmacy, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Reactions of morpholine, piperidine, and piperazine with Os(VIII)-catalyzed hexacyanoferrate(III) in alkaline media to produce the corresponding lactam have been studied at constant temperature and ionic strength. The reactions followed first-order kinetics with respect to [amine] and [Os(VIII)] but were independent of [Fe(CN)6 3-] and [OH-]. The effects of introduced electrolytes, potassium hexacyanoferrate(II), relative permitivity, and temperature have also been studied. A mechanism accounting for these results has been proposed.

Oxidation of some Alicyclic Amines by Potassium Hexacyanoferrate (III) in Alkaline Medium: A Kinetic and Mechanistic Study

Wed, 2014-04-02 12:22 — Dr. Waheed J. Jondi

Journal Title, Volume, Page:

An-Najah University Journal for Research - Natural Sciences - Volume 15, Issue 1

Year of Publication:

2001

Link:

http://scholar.najah.edu/publication/journal-article/oxidation-some-alicyclic-am...

Authors:

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hanoun

College of Pharmacy, An-Najah National University, Nablus, Palestine

M. J. Mus

College of Pharmacy, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Oxidation of some alicyclic amines (morpholine, piperazine and piperidine) by potassium hexacyanoferrate(III) in basic medium has been investigated at 35°C. Stoichiometric results showed that four moles of hexacyanoferrate(III) were consumed per mole of piperidine or morpholine whereas piperazine consumed eight moles of the oxidant to produce the corresponding lactams. Kinetic studies indicated that piperidine and morpholine also followed different kinetics from that of piperazine, being first order in the amine concentration and independent of the concentrations of hexacyanoferrate(III) and hydroxide ion, while in the case of piperazine, the reaction was first order in both oxidant and substrate concentrations and zero order with respect to the concentration of hydroxide ion. The changes in reaction rate due to changing ionic strength of the medium as well as other factors has also been investigated. The activation parameters of the oxidation process have been evaluated and a mechanism consistent with the observed kinetics has been proposed.

Osmium(VIII)-Catalyzed Oxidation of Some Cyclic Amines by Potassium Hexacyanoferrate(III) in Alkaline Media: a Kinetics and Mechanistic Study

Mon, 2014-02-03 10:36 — Mohammad Musmar

Journal Title, Volume, Page:

Chemistry of Heterocyclic Compounds April 2003, Volume 39, Issue 4, pp 478-484

Year of Publication:

2003

Link:

http://link.springer.com/article/10.1023%2FA%3A1024765330259

Authors:

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hannoun

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

M. J. Musmar

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

[email protected]

Preferred Abstract (Original):

Reactions of morpholine, piperidine, and piperazine with Os(VIII)-catalyzed hexacyanoferrate(III) in alkaline media to produce the corresponding lactam have been studied at constant temperature and ionic strength. The reactions followed first-order kinetics with respect to [amine] and [Os(VIII)] but were independent of [Fe(CN)₆ ^3-] and [OH^-]. The effects of introduced electrolytes, potassium hexacyanoferrate(II), relative permitivity, and temperature have also been studied. A mechanism accounting for these results has been proposed.

Oxidation of some Alicyclic Amines by Potassium Hexacyanoferrate (III) in Alkaline Medium: A Kinetic and Mechanistic Study

Mon, 2014-02-03 10:16 — Mohammad Musmar

Journal Title, Volume, Page:

Journal of Molecular Catalysis A Chemical. 10/2013; 39(1):1-11

Year of Publication:

2013

Authors:

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hanoun

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

M. J. Musmar

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

[email protected]

Preferred Abstract (Original):

Oxidation of some alicyclic amines (morpholine, piperazine and piperidine) by potassium hexacyanoferrate( ) in basic medium has been investigated at 35 ° C. Stoichiometric results showed that four moles of hexacyanoferrate(III) were consumed per mole of piperidine or morpholine whereas piperazine consumed eight moles of the oxidant to produce the corresponding lactams. Kinetic studies indicated that piperidine and morpholine also followed different kinetics from that of piperazine, being first order in the amine concentration and independent of the concentrations of hexacyanoferrate( ) and hydroxide ion, while in the case of piperazine, the reaction was first order in both oxidant and substrate concentrations and zero order with respect to the concentration of hydroxide ion. The changes in reaction rate due to changing ionic strength of the medium as well as other factors has also been investigated. The activation parameters of the oxidation process have been evaluated and a mechanism consistent with the observed kinetics has been proposed.

Oxidation of Some Alicyclic Amines by Potassium Hexacyanoferrate (III) In Alkaline Medium: A Kinetic and Mechanistic Study

Thu, 2014-01-30 14:59 — Mohammad Musmar

Journal Title, Volume, Page:

An-Najah University Journal for Research - Natural Sciences - Volume 15, Issue 1, 2001

Year of Publication:

2001

Link:

http://scholar.najah.edu/publication/journal-article/oxidation-some-alicyclic-am...

Authors:

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hanoun

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

M. J. Mus

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

[email protected]

Preferred Abstract (Original):

Oxidation of some alicyclic amines (morpholine, piperazine and piperidine) by potassium hexacyanoferrate(III) in basic medium has been investigated at 35°C. Stoichiometric results showed that four moles of hexacyanoferrate(III) were consumed per mole of piperidine or morpholine whereas piperazine consumed eight moles of the oxidant to produce the corresponding lactams. Kinetic studies indicated that piperidine and morpholine also followed different kinetics from that of piperazine, being first order in the amine concentration and independent of the concentrations of hexacyanoferrate(III) and hydroxide ion, while in the case of piperazine, the reaction was first order in both oxidant and substrate concentrations and zero order with respect to the concentration of hydroxide ion. The changes in reaction rate due to changing ionic strength of the medium as well as other factors has also been investigated. The activation parameters of the oxidation process have been evaluated and a mechanism consistent with the observed kinetics has been proposed.

Oxidation of some Alicyclic Amines by Potassium Hexacyanoferrate (III) in Alkaline Medium: A Kinetic and Mechanistic Study

Mon, 2014-01-06 10:01 — Mohammed Al-Subu'

Journal Title, Volume, Page:

An-Najah University Journal for Research - Natural Sciences - Volume 15, Issue 1, 2001

Year of Publication:

2001

Link:

http://scholar.najah.edu/publication/journal-article/oxidation-some-alicyclic-am...

Authors:

M.M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hanoun

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M.J. Musmar

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Oxidation of some alicyclic amines (morpholine, piperazine and piperidine) by potassium hexacyanoferrate(???) in basic medium has been investigated at 35°C. Stoichiometric results showed that four moles of hexacyanoferrate(III) were consumed per mole of piperidine or morpholine whereas piperazine consumed eight moles of the oxidant to produce the corresponding lactams. Kinetic studies indicated that piperidine and morpholine also followed different kinetics from that of piperazine, being first order in the amine concentration and independent of the concentrations of hexacyanoferrate(???) and hydroxide ion, while in the case of piperazine, the reaction was first order in both oxidant and substrate concentrations and zero order with respect to the concentration of hydroxide ion. The changes in reaction rate due to changing ionic strength of the medium as well as other factors has also been investigated. The activation parameters of the oxidation process have been evaluated and a mechanism consistent with the observed kinetics has been proposed. Keywords: Hexacyanoferrate(???), morpholine, piperazine, piperidine, oxidation, lactam

Osmium(VIII)-Catalyzed Oxidation of Some Cyclic Amines by Potassium Hexacyanoferrate(III) in Alkaline Media: a Kinetics and Mechanistic Study

Sun, 2014-01-05 14:40 — Mohammed Al-Subu'

Journal Title, Volume, Page:

Chemistry of Heterocyclic Compounds April 2003, Volume 39, Issue 4, pp 478-484

Year of Publication:

2003

Link:

http://link.springer.com/article/10.1023/A%3A1024765330259

Authors:

M. M. Al-Subu

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

W. J. Jondi

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

A. A. Amer

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. Hannoun

Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine

M. J. Musmar

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

Reactions of morpholine, piperidine, and piperazine with Os(VIII)-catalyzed hexacyanoferrate(III) in alkaline media to produce the corresponding lactam have been studied at constant temperature and ionic strength. The reactions followed first-order kinetics with respect to [amine] and [Os(VIII)] but were independent of [Fe(CN)₆ ^3-] and [OH^-]. The effects of introduced electrolytes, potassium hexacyanoferrate(II), relative permitivity, and temperature have also been studied. A mechanism accounting for these results has been proposed.