Anticandidal activity

mohammed-alnuri's picture

Antimicrobial Activity of 20 Plants Used in Folkloric ‎Medicine in the Palestinian Area

Journal Title, Volume, Page: 
Journal of Ethnopharmacology Volume 60, Issue 3, Pages 265–271
Year of Publication: 
1998
Authors: 
M.A Al-Nuri
Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine
Y.R Faidi
Department of Medical Technology, An-Najah National University, Nablus, Palestine
M.S Ali-Shtayeh
Department of Biological Sciences, An-Najah National University, Nablus, Palestine
Reem M.-R Yaghmour
Department of Biological Sciences, An-Najah National University, Nablus, Palestine
Khalid Salem
Department of Biology, Al-Quds University, Abu Dis, Palestine
Preferred Abstract (Original): 

Ethanolic and aqueous extracts of 20 Palestinian plant species used in folk medicine were investigated for their antimicrobial activities against five bacterial species (Staphylococcus aureusEscherichia coli,Klebsiella pneumoniaeProteus vulgarisPseudomonas aeruginosa) and one yeast (Candida albicans). The plants showed 90% of antimicrobial activity, with significant difference in activity between the different plants. The most antimicrobially active plants were Phagnalon rupestre and Micromeria nervosa, whereas, the least active plant was Ziziphus spina-christi. Only ten of the tested plant extracts were active against C. albicans, with the most active from M. nervosa and Inula viscosa and the least active from Ruscus aculeatus. Of all extracts the ethanolic extract of M. nervosa was the most active, whereas, the aqueous extract of Phagnalon rupestre was the most active of all aqueous extracts tested. The ethanolic extracts (70%) showed activity against both Gram positive and negative bacteria and 40% of these extracts showed anticandidal activity, whereas, 50% of the aqueous extracts showed antibacterial activity and 20% of these extracts showed anticandidal activity.

adwank's picture

Assessment of Antifungal Activity of Herbal and Conventional Toothpastes against Clinical Isolates of Candida Albicans

Journal Title, Volume, Page: 
Asian Pacific Journal of Tropical Biomedicine Volume 2, Issue 5, May 2012, Pages 375–379
Year of Publication: 
2012
Authors: 
Ghaleb Adwan
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Yousef Salameh
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Kamel Adwan
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Ali Barakat
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine
Preferred Abstract (Original): 

To detect the anticandidal activity of nine toothpastes containing sodium fluoride, sodium monofluorophosphate and herbal extracts as an active ingredients against 45 oral and non oral Candida albicans (C. albicans) isolates.
Methods The antifungal activity of these toothpaste formulations was determined using a standard agar well diffusion method. Statistical analysis was performed using a statistical package, SPSS windows version 15, by applying mean values using one-way ANOVA with post-hoc least square differences (LSD) method. A P value of less than 0.05 was considered significant.
Results All toothpastes studied in our experiments were effective in inhibiting the growth of all C. albicans isolates. The highest anticandidal activity was obtained from toothpaste that containing both herbal extracts and sodium fluoride as active ingredients, while the lowest activity was obtained from toothpaste containing sodium monofluorophosphate as an active ingredient. Antifungal activity of Parodontax toothpaste showed a significant difference (P< 0.001) against C. albicans isolates compared to toothpastes containing sodium fluoride or herbal products.
Conclusions In the present study, it has been demonstrated that toothpaste containing both herbal extracts and sodium fluoride as active ingredients are more effective in control of C. albicans, while toothpaste that containing monofluorophosphate as an active ingredient is less effective against C. albicans. Some herbal toothpaste formulations studied in our experiments, appear to be equally effective as the fluoride dental formulations and it can be used as an alternative to conventional formulations for individuals who have an interest in naturally-based products. Our results may provide invaluable information for dental professionals.

MSShtayeh's picture

Antimicrobial Activity of 20 Plants Used In Folkloric Medicine in the Palestinian Area

Journal Title, Volume, Page: 
Journal of Ethnopharmacology Volume 60, Issue 3, April 1998, Pages 265–271
Year of Publication: 
1998
Authors: 
M.S Ali-Shtayeh
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus. Palestine
Current Affiliation: 
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus. Palestine
Reem M.-R Yaghmour
Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus. Palestine
Y.R Faidi
Department of Medical Technology, An-Najah National University, Nablus. Palestine
Khalid Salem
Department of Biology, Al-Quds University, Palestine
M.A Al-Nuri
Department of Chemistry, Faculty of Science, An-Najah National University, Nablus. Palestine
Preferred Abstract (Original): 

Ethanolic and aqueous extracts of 20 Palestinian plant species used in folk medicine were investigated for their antimicrobial activities against five bacterial species (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa) and one yeast (Candida albicans). The plants showed 90% of antimicrobial activity, with significant difference in activity between the different plants. The most antimicrobially active plants were Phagnalon rupestre and Micromeria nervosa, whereas, the least active plant was Ziziphus spina-christi. Only ten of the tested plant extracts were active against C. albicans, with the most active from M. nervosa and Inula viscosa and the least active from Ruscus aculeatus. Of all extracts the ethanolic extract of M. nervosa was the most active, whereas, the aqueous extract of Phagnalon rupestre was the most active of all aqueous extracts tested. The ethanolic extracts (70%) showed activity against both Gram positive and negative bacteria and 40% of these extracts showed anticandidal activity, whereas, 50% of the aqueous extracts showed antibacterial activity and 20% of these extracts showed anticandidal activity.

2038's picture

Assessment of Antifungal Activity of Herbal and Conventional Toothpastes Against Clinical Isolates of Candida Albicans

Journal Title, Volume, Page: 
Asian Pacific Journal of Tropical Biomedicine
Year of Publication: 
2012
Authors: 
Ali Barakat
Statistics Department, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Current Affiliation: 
Department of Statistics, An-Najah National University, Nablus, Palestine
Ghaleb Adwan
Department of Biology and Biotechnology, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Yousef Salameh
Department of Biology and Biotechnology, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Kamel Adwan
Department of Biology and Biotechnology, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Preferred Abstract (Original): 

Objective

To detect the anticandidal activity of nine toothpastes containing sodium fluoride, sodium monofluorophosphate and herbal extracts as an active ingredients against 45 oral and non oral Candida albicans (C. albicans) isolates.

Methods

The antifungal activity of these toothpaste formulations was determined using a standard agar well diffusion method. Statistical analysis was performed using a statistical package, SPSS windows version 15, by applying mean values using one-way ANOVA with post-hoc least square differences (LSD) method. A P value of less than 0.05 was considered significant.

Results

All toothpastes studied in our experiments were effective in inhibiting the growth of all C. albicans isolates. The highest anticandidal activity was obtained from toothpaste that containing both herbal extracts and sodium fluoride as active ingredients, while the lowest activity was obtained from toothpaste containing sodium monofluorophosphate as an active ingredient. Antifungal activity of Parodontax toothpaste showed a significant difference (P< 0.001) against C. albicans isolates compared to toothpastes containing sodium fluoride or herbal products.

Conclusions

In the present study, it has been demonstrated that toothpaste containing both herbal extracts and sodium fluoride as active ingredients are more effective in control of C. albicans, while toothpaste that containing monofluorophosphate as an active ingredient is less effective against C. albicans. Some herbal toothpaste formulations studied in our experiments, appear to be equally effective as the fluoride dental formulations and it can be used as an alternative to conventional formulations for individuals who have an interest in naturally-based products. Our results may provide invaluable information for dental professionals.

adwang's picture

Assessment of Antifungal Activity of Herbal And Conventional Toothpastes Against Clinical Isolates of Candida Albicans

Journal Title, Volume, Page: 
Asian Pacific Journal of Tropical Biomedicine (2012); 2(5):375-379
Year of Publication: 
2012
Authors: 
Ghaleb Adwan
Department of Biology and Biotechnology, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Current Affiliation: 
Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine
Yousef Salameh
Department of Biology and Biotechnology, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Kamel Adwan
Department of Biology and Biotechnology, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Ali Barakat
Statistics Department, An-Najah N. University, P. O. Box (7)-Nablus, Palestine
Preferred Abstract (Original): 
Objective: To detect the anticandidal activity of nine toothpastes containing sodium fluoride, sodium monofluorophosphate and herbal extracts as an active ingredients against 45 oral and non oral Candida albicans (C. albicans) isolates. Methods: The antifungal activity of these toothpaste formulations was determined using a standard agar well diffusion method. Statistical analysis was performed using a statistical package, SPSS windows version 15, by applying mean values using one-way ANOVA with post-hoc least square differences (LSD) method. A P value of less than 0.05 was considered significant. Results: All toothpastes studied in our experiments were effective in inhibiting the growth of all C. albicans isolates. The highest anticandidal activity was obtained from toothpaste that containing both herbal extracts and sodium fluoride as active in gredients, while the lowest activity was obtained from toothpaste containing sodium monofluorophosphate as an active ingredient. Antifungal activity of Parodontax toothpaste showed a significant difference (P< 0.001) against C. albicans isolates compared to toothpastes containing sodium fluoride or herbal products. Conclusions: In the present study, it has been demonstrated that toothpaste containing both herbal extr acts and sodium fluoride as active ingredients are more effective in control of C. albicans, while toothpaste that containing monofluorophosphate as an active ingredient is less effective against C. albicans. Some herbal toothpaste formulations studied in our experiments, appear to be equally effective as the fluoride dental formulations and it can be used as an alternative to conventional formulations for individuals who have an interest in naturally-based products. Our results may provide invaluable information for dental professionals.
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