Health-Related Quality of Life Associated with Treatment Adherence in Patientswith Hypertension: A Cross-Sectional Study

Waleed Sweileh's picture
Journal Title, Volume, Page: 
Int J Cardiol. 2013 May 3. pii: S0167-5273(13)00692-X. doi: 10.1016/j.ijcard.2013.04.105. [Epub ahead of print]
Year of Publication: 
2013
Authors: 
Waleed M. Sweileh
Department of Pharmacology and Toxicology, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Current Affiliation: 
College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Sa'ed H. Zyoud
Poison Control and Drug Information Center (PCDIC), College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Samah W. Al-Jabi
Department of Clinical Pharmacy and Pharmacotherapy, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Aysha H. Wildali
PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Hanan M. Saleem
PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Hayat A. Aysa
PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Mohammad A. Badwan
PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Rahmat Awang
WHO Collaborating Centre for Drug Information, National Poison Centre, Universiti Sains Malaysia (USM), Penang, Malaysia
Donald E. Morisky
Department of Community Health Sciences, UCLA School of Public Health, Los Angeles, CA, USA
Preferred Abstract (Original): 

Hypertension is one of the most important risk factors for coronary heart disease, heart failure, renal failure and stroke, and it remains an important public health challenge which contributes to disability, health care costs and mortality [1] and [2]. The concepts of medication adherence and health-related quality of life (HRQoL) are commonly used in clinical research for assessing pharmaceutical care and improving treatment outcomes [3]. Adherence to drug treatment usually refers to the extent to which patients follow the instructions of their physician or health care providers. HRQoL also refers to the physical, psychological and social dimensions of health that are influenced by a person's experiences, beliefs, expectations and perceptions [4]. Generally one would expect a positive relationship between the two concepts. The objective of this study was to examine the relationship between adherence and HRQoL in a hypertensive population. Knowledge of any differences in HRQoL in this population may be helpful in the planning of therapeutic interventions that will ensure desirable HRQoL and not just the control of blood pressure. Knowledge of HRQoL in hypertensive patients and of the relationship between HRQoL and adherence, being a reliable determinant of cardiovascular disease (CVD) events, will be helpful in preventing or reducing the incidence of CVDs.

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