Objective: The aim of this study was to assess the
relationship between antihypertensive medication adherence and HRQoL. Methods:
A cross-sectional study was conducted, adopting the Morisky eight-item
Medication Adherence Scale (MMAS) for the assessment of medication adherence
and using the European Quality of Life scale (EQ-5D-5L) for the assessment of
HRQoL. Descriptive and comparative statistics were used to describe
socio-demographic and disease-related characteristics of the patients. All
analyses were performed using SPSS v 15.0.
Results: Four hundred and ten
hypertensive patients were enrolled in the study. The mean age of participants
was 58.38 ± 10.65 years; 52% were female and 36.8% had low antihypertensive
medication adherence. Patients with a high adherence rate had the highest HRQoL
scores compared with those with a low or medium adherence rate (Kruskal–Wallis
test; p < 0.05). After adjustment for covariates using multiple regression,
HRQoL was still statistically significantly associated with medication
adherence (p = 0.001). Conclusions: Low HRQoL may be an important barrier to
achieving high rates of adherence to treatment. These study findings could be
helpful in clinical practice, mainly in the early treatment of hypertensive
patients, at a point where improving HRQoL is still possible.
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Health-Related_Quality_of_Life_Associated_With_Treatment_Adherence_in_Patients_with_Hypertension_A_Cross-Sectional_Study.pdf | 63.91 KB |