Home › mohammed-alnuri › Publications › Published Researches

Antimicrobial Activity of Micromeria Nervosa from the ‎Palestinian Area

mohammed-alnuri's picture
Tue, 2014-04-01 07:42 — Mohammed Abdullah Al-Nuri
Journal Title, Volume, Page: 
Journal of Ethnopharmacology Volume 58, Issue 3, Pages 143–147
Year of Publication: 
1997
Link: 
http://www.sciencedirect.com/science/article/pii/S0378874197000883
Authors: 
M.A. Al-Nuri
Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine
[email protected]
M.S. Ali-Shtayeh
Department of Biological Sciences, An-Najah National University, Nablus, Palestine
Reem M.-R. Yaghmour
Department of Biological Sciences, An-Najah National University, Nablus, Palestine
Y.R. Faidi
Department of Medical Technology, An-Najah National University, Nablus, Palestine
Preferred Abstract (Original): 

Organic and aqueous solvent extracts and fractions of Micromeria nervosa (Desf.) Benth. (Labiatae) were investigated for antimicrobial activities on several microorganisms including bacteria and yeast. The different extracts differed significantly in their antimicrobial activities with the ethanolic extract being most active, followed by ethyl acetate and petroleum ether extracts. The least active extract was the aqueous. No significant difference between the different test microorganisms in their susceptibility to different extracts, with Candida albicans being the most susceptible to ethanolic extract giving 1.5 times the effect of nystatin. One of the main active ingredients of M. nervosa was isolated and identified as carvacrol. No significant difference in antimicrobial activity was found between carvacrol and its isomer thymol. The most susceptible test microorganism was Proteus vulgaris to carvacrol, and P. vulgaris and C. albicans to thymol. The least susceptible bacterium to both fractions was Pseudomonas aeruginosa. Minimum inhibitory concentration (MIC) and minimum bactericidal or fungicidal concentrations (MBC or MFC) were determined for both compounds.