magnetic resonance enterography

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Ultra–High-Field Magnetic Resonance Enterography In The Diagnosis of Ileitis (Neo-) Terminalis A Prospective Study

Journal Title, Volume, Page: 
J Clin Gastroenterol. 2012 Apr;46(4):311-6. doi: 10.1097/MCG.0b013e31822fec0c.
Year of Publication: 
2012
Authors: 
Henning Ernst Adamek
2nd Med. Department, Klinikum Leverkusen, University Hospital of Cologne, Cologne
Walburga Schantzen
Radiology Network Rheinland, Leverkusen, Germany
Ulf Rinas
2nd Med. Department, Klinikum Leverkusen, University Hospital of Cologne, Cologne
Matthias Goyen
UKE Consult and Management GmbH, Martinistrabe, Hamburg, Germany
Waled Ajaj
2nd Med. Department, Klinikum Leverkusen, University Hospital of Cologne, Cologne, Germany
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Christina Esser
2nd Med. Department, Klinikum Leverkusen, University Hospital of Cologne, Cologne
Preferred Abstract (Original): 

Background and Goals: Magnetic resonance (MR) enterography provides the advantages of conventional enteroclysis and those of cross-sectional imaging. Adequate luminal distension, combined with ultrafast sequences, results in excellent delineation of mural and extramural manifestations of Crohn's disease. Recent technical advances, including ultra-high-field strength MR with its capability to provide fast multiplanar images with excellent soft tissue contrast, are only rarely included in abdominal studies.
Study: One hundred four consecutive patients with a proved or suspected diagnosis of ileitis terminalis were prospectively selected for MR imaging studies and ileocolonoscopy. The final diagnosis was based on histopathological findings or based on a combined endpoint of clinical, laboratory, endoscopic, and imaging findings.
Results: According to the endoscopic examination, stenosis was present in 26 patients (25%) and could be ruled out in 78 patients (75%). Total agreement between MR and endoscopy could be reached in 74 patients (71%). Histology indicated absence of inflammation in 50 patients (48%). MR and endoscopic findings were concordant in 38 patients (76%) and 37 patients (74%), respectively. Corresponding results by ileocolonoscopy were 37 true negative, 29 true positive, 4 false positive, and 12 false negative (sensitivity, 70.7%; specificity, 74%).
Conclusions: MR enterography with a 3.0-T scanner is a powerful tool in the evaluation of ileal diseases, and has therefore made MR enterography the first-line modality at our institution in patients with suspected inflammatory bowel disease.

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