Colorectal pathologies

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Colonography By Magnetic Resonance Imaging

Journal Title, Volume, Page: 
European Journal of Gastroenterology & Hepatology. 17(8):815-820, August 2005
Year of Publication: 
2005
Authors: 
Waleed Ajaj
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Germany
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Jorg F. Debat in
University Hospital Hamburg -Eppendorf, Germany
Thomas Lauenstein
Department of Diagnostic and Interventional Radiology, University Hospital Essen, Germany
Preferred Abstract (Original): 
Dark-lumen magnetic resonance colonography has been shown to be an appropriate diagnostic tool for the detection of colorectal pathologies. This review describes the underlying techniques of dark-lumen magnetic resonance colonography concerning data acquisition, image interpretation and diagnostic accuracy for the detection of colorectal pathologies. In addition, techniques to improve patients' acceptance are discussed.
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MR Colonography With Parallel Acquisition Techniques To Increase Spatial Resolution: A Feasibility Study

Journal Title, Volume, Page: 
Proc. Intl. Soc. Mag. Reson. Med. 13 (2005)
Year of Publication: 
2005
Authors: 
C. A. Kuehle
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
Waleed Ajaj
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
K. Reiter
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
S. Maderwald
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
S. C. Ladd
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
J. Barkhausen
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
T. C. Lauenstein
Institute of Diagnostic and Interventional Radiology, University Hospital of Essen, Essen, NRW, Germany
Preferred Abstract (Original): 

Magnet resonance colonography (MRC) is a promising method for the depiction of colorectal pathologies. For colorectal masses exceeding 10mm, high accuracy values (92% to 100%) have been reported (1). However, due to limited spatial resolution, the detection rate of smaller pathologies is only fair. Another limitation of current MRC protocols is related to relatively long data acquisition of up to 25 seconds, which need to be performed under breath-hold conditions. Especially in elderly patients or patients with diseases of the respiratory tract, this can result in severe motion artefacts hampering a reliable assessment of the colon. The underlying problems may be solved by new image acquisition techniques providing a higher spatial resolution and / or a decreased acquisition time. These parallel acquisition techniques (PAT) have recently been successfully applied for MR colonography in an in-vitro study (2). Aim of the current trial was to prove the practicability of PAT imaging for MR colonography in-vivo.

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Utility of Dark-Lumen MR Colonography For The Assessment of Extra-Colonic Organs

Journal Title, Volume, Page: 
Eur Radiol (2007) 17: 1574–1583
Year of Publication: 
2007
Authors: 
Waleed Ajaj
Medical Center, University Hospital Hamburg-Eppendorf, Martini-Straße 52, 22046, Hamburg, Germany
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Stefan G. Ruehm
David Geffen School of Medicine, Department of Radiology, University of California-Los Angeles, Los Angeles, USA
Susanne C. Ladd
Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany
Guido Gerken
Department of Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany
Mathias Goyen
Medical Center, University Hospital Hamburg-Eppendorf, Martini-Straße 52, 22046, Hamburg, Germany
Preferred Abstract (Original): 

The aim of the study was to evaluate the utility of dark-lumen MR colonography (MRC) for the assessment of extra-colonic organs. Three hundred seventy-five subjects with suspected colonic disease underwent a complete MRC examination. MRC data were evaluated by two radiologists in a blinded fashion. In addition to the large bowel, the extra-intestinal organs from the lung bases to the pelvis were assessed for the presence of pathologies. All findings were divided into known or unknown findings and therapeutically relevant or irrelevant findings. If deemed necessary, other diagnostic imaging tests to further assess those findings were performed. In total, 510 extracolonic findings were found in 260 (69%) of the 375 subjects. Known extra-colonic findings were found in 140 subjects (54%) and unknown findings in 120 subjects (46%). Thirty-one (12%) of the 260 subjects had therapeutically relevant findings (45 findings); 229 patients (88%) had irrelevant findings (465 findings). Dark-lumen MRC is a useful tool not only for the assessment of the entire colon, but also for the evaluation of extra-colonic organs. Thus, intra- and extra-colonic pathologies can be diagnosed within the same examination.

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MR Imaging of The Colon: “Technique, Indications, Results And Limitations”

Journal Title, Volume, Page: 
European Journal of Radiology 61 (2007) 415–423
Year of Publication: 
2007
Authors: 
Waleed Ajaj
University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Mathias Goyen
University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Preferred Abstract (Original): 

In the last few years virtual colonography using MR imaging has shown a proceeding development regarding detection and quantification of colorectal pathologies. Dark-lumen MR colonography (MRC) has been a leading tool for the diagnosis of the entire colon and their pathologies. This review article describes some of the underlying techniques of MRC concerning data acquisition, the need for intravenously applied paramagnetic contrast agent, as well as indications, results and limitations of MRC for the detection of colorectal pathologies. In addition, new techniques to improve patient acceptance are discussed.

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