ALCOHOL

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The Prevalence of alcohol and Psychotropic drugs in fatalities of road-traffic accidents in Jordan during 2008 – 2014

Journal Title, Volume, Page: 
Journal of Forensic and Legal Medicine · January 2016, DOI: 10.1016/j.jflm.2016.01.018
Year of Publication: 
2016
Authors: 
Imad M. AL-Abdallat
Faculty of Medicine, Department of Pathology and Microbiology and Forensic Medicine, The University of Jordan, Jordan University Hospital, Amman, Jordan
Rayyan Al Ali
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestin
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestin
Arwa A. Hudaib
The University of Jordan, Amman, Jordan
Ghada A.M. Salameh
The University of Jordan, Amman, Jordan
Rakiz J.M. Salameh
The University of Jordan, Amman, Jordan
Ahmed K.F. Idhair
The University of Jordan, Amman, Jordan
Preferred Abstract (Original): 

Objective Several studies confirmed alcohol and psychotropic drug consumption as important risk factors underlying fatal accidents. This paper presents updated toxicological findings in the fatalities of road traffic accidents of Amman district, in order to have an overall picture of the occurrence of these substances in these victims in Jordan. Method Over a seven-year period (2008–2014), 2743, autopsies were conducted at Jordan University Hospital in which the sum of n = 311 (11.38%) were victims of road traffic accidents. Blood samples from these victims were collected. Toxicology screening for psychotropic drugs and alcohol was conducted on these samples, and the results were analyzed according to age, sex and victim's status.
Results This study revealed that Alcohol and psychotropic drugs were positive in 36.5%, (n = 58) of the cases, and for alcohol alone (n = 13, 37.1%). The majority of the victims were pedestrians (n = 155, 49.8%). Additionally, 29.6% (n = 92) of the cases were of ages 19–29. Detected psychotropic drugs were benzodiazepines, barbiturates. None of the collected specimens were positive for illicit cocaine, amphetamines or cannabis.
Conclusions The results from this study proved the existence of alcohol and psychotropic drugs in the victims of road traffic accidents; Indicating an association between the uses of these substances in accident involvement. Though having some limitations, other conclusions require further data collection, cooperation with related parties in Jordan, and utilizing simple extended toxicological screens.  

adwank's picture

Antibacterial Activities of Some Plant Extracts Utilized in Popular Medicine in Palestine

Journal Title, Volume, Page: 
Turkish Journal of Biology;2004, Vol. 28 Issue 2-4, p99
Year of Publication: 
2004
Authors: 
Abu-Shanab, Bassam
Faculty of Veterinary Medicine, An-Najah N. University, Nablus, Palestine
Adwan, Ghaleb
Department of Biological Sciences, An-Najah N. University, Nablus, Palestine
Abu-Safiya, Dahood
Faculty of Agriculture, An-Najah N. University, Nablus, Palestine
Jarrar, Naser
Department of Biological Sciences, An-Najah N. University, Nablus, Palestine
Adwan, Kamel
Department of Biological Sciences, An-Najah N. University, Nablus, Palestine
Current Affiliation: 
Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine
Preferred Abstract (Original): 

The antibacterial activities of hot water, methanol and ethanol extracts of 5 plant extracts utilized in Palestine in popular medicine were studied. The dried extracts of Syzyium aromaticum (Myrtaceae) (seed), Cinnamomum cassia (Lauraceae) (cassia bark, Chinese cinnamon) (bark), Salvia officinalis (Lamiaceaea) (leaf), Thymus vulgaris (Lamiaceaea) (leaf) and Rosmarinus officinalis (Labiatae) (leaf) were tested in vitro against 4 bacterial species by disk diffusion and micro-dilution. The patterns of inhibition varied with the plant extract, the solvent used for extraction, and the organism tested. Methicillin-resistant Staphylococcus aureus (MRSA) and Bacillus subtilis ATCC 6633 were the most inhibited microorganisms. S. aromaticum extract was the most active against multidrug resistant Pseudomonas aeruginosa and enterohemorrhagic Escherichia coli O157 EHEC. The combinations of ethanolic extracts of S. officinalis with R. officinalis and of R. officinalis with T. vulgaris on bacterial species tested exhibited a higher effect than that of any individual extract. Results of this kind herald the interesting promise of designing a potentially active antibacterial synergized agent of plant origin.

Iyad Ali's picture

Synthesis of Selective β-lactam Derivatives

Journal Title, Volume, Page: 
An - Najah Univ. J. Res. (N. Sc.) Vol. 27, 2013
Year of Publication: 
2013
Authors: 
Iyad Ali
Faculty of Medicine & Health Sciences, An-Najah National University, Palestine
Current Affiliation: 
Faculty of Medicine & Health Sciences, Department of Biomedical Sciences, An-Najah National University, Nablus, Palestine
Nina Sakhnini
Preferred Abstract (Original): 

In this work, the mild conditions of Mitsunobu reaction were used to convert the hydroxyl group of 6-triphenylmethylaminopenicillanyl alcohol to amines by using different nuleophiles such as phthalimide, di-tert-butyliminodicarboxylate and potassium cyanate. The existence of the β-lactam carbonyl group increased the instability towards nucleophilic attack of refluxing methanol and the four-membered ring was opened. Treating 3-Di-tert-Butoxycarbonylaminomethyl-6-triphenylmethylamino - penicillanate with 50% trifluoroacetic acid in dichloromethane, resulted in the cleavage of triphenylmethyl group and one tert-butyl group. While the removal of both triphenylmethyl groups as well as di-tert-butylamino carbonyl group occurred when 75% trifluoroacetic acid was used. The significance of this study is to synthesize β-lactam derivatives that might to be more resistant to degradation by β-lactamase and hence, therapeutically more effective.

adwang's picture

Antibacterial Activities of Some Plant Extracts Utilized In Popular Medicine In Palestine

Journal Title, Volume, Page: 
Turk J Biol 28 (2004) 99-102
Year of Publication: 
2004
Authors: 
Bassam Abu-Shanab
Faculty of Veterinary Medicine, An-Najah N. University, Nablus, Palestine
Ghaleb Adwan
Department of Biological Sciences, An-Najah N. University, Nablus, Palestine
Current Affiliation: 
Department of Biology, Faculty of Science, An-Najah National University, Nablus. Palestine
Dahood Abu-Safiya
Faculty of Agriculture, An-Najah N. University, Nablus, Palestine
Naser Jarrar
Department of Biological Sciences, An-Najah N. University, Nablus, Palestine
Kamel Adwan
Department of Biological Sciences, An-Najah N. University, Nablus, Palestine
Preferred Abstract (Original): 

The antibacterial activities of hot water, methanol and ethanol extracts of 5 plant extracts utilized in Palestine in popular medicine were studied. The dried extracts of Syzyium aromaticum (Myrtaceae) (seed), Cinnamomum cassia (Lauraceae) (cassia bark, Chinese cinnamon) (bark), Salvia officinalis (Lamiaceaea) (leaf), Thymus vulgaris (Lamiaceaea) (leaf) and Rosmarinus officinalis (Labiatae) (leaf) were tested in vitro against 4 bacterial species by disk diffusion and micro-dilution. The patterns of inhibition varied with the plant extract, the solvent used for extraction, and the organism tested. Methicillin-resistant Staphylococcus aureus (MRSA) and Bacillus subtilis ATCC 6633 were the most inhibited microorganisms. S. aromaticum extract was the most active against multidrug resistant Pseudomonas aeruginosa and enterohemorrhagic Escherichia coli O157 EHEC. The combinations of ethanolic extracts of S. officinalis with R. officinalis and of R. officinalis with T. vulgaris on bacterial species tested exhibited a higher effect than that of any individual extract. Results of this kind herald the interesting promise of designing a potentially active antibacterial synergized agent of plant origin.

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