General Microbiology

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Course Code: 
140431
Course Outline: 
140431 General Microbiology
Course Credit Hours: 4
Students Workload: 4
Teacher workload: 4
PREREQUISITES
-
CO REQUISITES
-
TIME AND LOCATION
 
 
 
INSTRUCTORS
Name, Title:    Walid Basha, PhD
Office address:
Office hours:  
Phone: 0599590284
Email: wbasha@najah.edu
 
TEXT BOOK:
Greenwood David et al. Medical Microbiology 17th Ed 2007
 
REFERENCES
Published scientific papers.
 
ADDITIONAL MATERIALS OR EQUIPMENT NEEDED FOR THE COURSE
Medical laboratory materials
Internet resources
 
SUPPLEMENTARY MATERIALS
Reviews and articles from the international journals on the web
The references in the library of the University
Commercial Microbiology Kit manuals
 
COURSE DESCRIPTION
The course is designed to give medical students with detailed concepts in general microbiology. Diversity of micro-organisms; evolutionary relationships and taxonomy(viruses, bacteria, fungi and parasites); principles of culture, staining, microscopy, sterilization of media and equipment; the cultural, morphological, biochemical characteristics and identification scheme for bacteria, fungi, parasites and viruses; principles of pathogenicity and defence mechanisms (immunity).
 
INTENDED LEARNING OUTCOMES
This course will provide students with Knowledge on various sub-disciplines of Microbiology.After this course the students should know and understand all scientific disciplines of microscopes; be able to describe diversity of microorganisms; explain the basic genetic systems of bacteria; explain the ability of microorganisms to cause disease and demonstrate practical skills in fundamental microbiological techniques.The student should be familiar with different categories of microorganisms including bacteria, viruses, parasites & fungi regarding taxonomy, structure, growth characteristics & replication of each microbial group.
 
Intended Learning Outcomes of Course (ILOs)
a- Knowledge and Understanding:
a.1. Recognize microbial taxonomic classification, structure  and morphology.
a.2. Describe microbial metabolism.
a.3. Differentiate between Gram positive, Gram negative and acid fast organism.
a.4. Be familiar with different media for isolation and identification of different organisms.
a.5. Distinguish microbial genetics and the uses of genetic engineering.
a.6. Describe the antibiotic sensitivity against different organisms
a.7.Define different methods of disinfections & sterilization.
a.8. Make out the different levels of host-parasite relationship
a.9.Recognize virulence factor of each organism
 
b- Intellectual Skills.
b.1. Differentiate between different types of microorganisms in the lab (Interpret smears, culture plate,  biochemical reaction).
b.2. Read sensitivity test on the culture plates.
b.3. Differentiate between different serological tests in lab.
 
c- Professional and Practical Skills:
c.1. Examination Gram stained or Ziehl Neelsen smears.
c.2. Examine different culture plates & Biochemical reaction.
c.3. Examine sensitivity plates.
c.4. Examine reaction to agglutination and precipitation.
 
d- General and transferable skills:
d.1. Search Internet data base for diagnostic measures in microbiology.
d.2. Independently learning
d.3. Follow measure for infections control.
d.4. Work in a team.
d.5. Respect assisting personal.
d.6. Appreciate team work in seminar.
 
COURSE OUTLINE AND CALENDER
THEORY PART

 

TOPICS
WEEKS/HOURS
Part  I:  Introduction to microbiology
                   History and scope of Microbiology
                    Microscopy and specimen preparation
                    Prokaryotic  and eukaryotic cell structure and function
4 hours
 
Part II: Microbial nutrition, growth and control
                    Microbial growth
                    Microbial Nutrition
                    Physical and Chemical agents controlling  
                    microorganisms
4 hours
 
Part III: Microbial Metabolism
                    Energy, enzymes and regulation
                    Energy release and conversion
                    The use of energy in metabolism
4 hours
 
Part IV: Microbial molecular biology and genetics
                    Genes structure, regulation and mutation
                    Genes expression and regulation
                    Microbial recombination and plasmid
                    Recombinant DNA technology
                    Microbial genomics
8 hours
 
FIRST HOUR EXAM
 
Part V: The viruses
                    Introduction and general characteristics
                    Bacteriophages
                    Viruses of eukaryotes
6 hours
PartVI: The diversity of the microbial world
                    Taxonomy and phylogeny
                    Archaea
                    Bacteria
                    Fungi and molds
                    Algae
                    protozoa
16 hours
 
SECOND HOUR EXAM
 
Part VII: Microbial diseases and their control
                    Pathogenicity of microorganisms
                    Antimicrobial agents
                    Clinical microbiology
                    The epidemiology of infectious diseases
                    Viral diseases
                    Bacterial diseases
                    Fungal protozoan diseases
14 hours
Part VIII: Food and industrial Microbiology
                   Microbiology of the food
                     Industrial microbiology and biotechnology
4 hours
FINAL EXAM
 
Total
60 hours
 
PRACTICAL PART
Will be covered in course of Laboratory Methods (140400)
Dry laboratory will cover the principles of microbiology diagnosis methods
 
 
TEACHING AND LEARNING METHODS:
 

 

Tool
Purpose
ILOs
Lectures
To explain the theoretical knowledge for each topic
a.1, a.2, a.3, a.4, a.5,
a.6, a.7, a.8, a.9
Small group discussion sessions and seminars
To answer the questions of the students and evaluate their notebooks and their knowledge
d. 4, d.5, d.6
Micro project (e.i. Review article)
To teach the students how to examine the references and periodicals
d.1, d.2, a.4, a.5, a.6
Dry Laboratory
To explain the practical knowledge for each topic
b.1, b.2, b.3, c.1, c.2, c.3, c.4, d.3
 
TEACHING RESOURCES:
White board
One lecture hall in the department.
Overhead projector
Computer
 
COURSE POLICIES
Class attendance (Participation)
Student must attend at least 75% of lecture
 
GRADING:
Seminars and review presentation 25%
Midterm Exam 20%
Participation 5%
Final Exam 50%