Formulation and Evaluation of the Chemical Stability of Povidone-Iodine in Some Trademarks ‎Cleaning Formulations

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Journal Title, Volume, Page: 
Int J Pharm Pharm Sci. ; 5(1): 46-48
Year of Publication: 
2013
Authors: 
Abdel Naser Zaid
Department of Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Current Affiliation: 
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Preferred Abstract (Original): 

Purpose: The aim of this study is to evaluate the chemical stability of Povidone-Iodine (PVP-I) after its incorporation into commercial cleaning formulations. Method: PVP-I was incorporated into five different trademarks of cleaning formulation designated F1through F5. Chemical stability of PVP-Ion months 0,1,2,3 and 4 was checked. pH, color, smell, and foam properties of the obtained cleaning formulations were tested. Results: PVP-I in Shampoo (F1) and hair & body wash (F2) was stable for more than 4 months, while in the shower gel (F3) and liquid soap (F4) was stable within the limit period of three month. The body wash (F5) was stable for only one month. The pH of the formulations remains constant during the entire period of the study. The foam volume and stability was comparable to that obtained from the starting trademarks. No change in smell or color of the cleaning formulations was observed. No sign of precipitate was observed within the entire period of study. Conclusion: Compounding PVP-I into cleaning trademarks in order to achieve disinfection and medical benefits can be followed. Cleaner industries should take seriously in consideration this issue to improve their selling.  

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