5th PFMR Biomedical Research Symposium

shawahna's picture
Research Title: 
Ascorbic acid reduces lead levels in broiler chicken blood and eggs
Country: 
Birzeit University, Palestine
Date: 
Thu, 2014-12-04
Research Abstract: 

The present study was conducted to determine the amount of lead (Pb) deposited in chicken blood, eggs and tissues after exposure to a concentrated source of Pb for 1 week and to determine the effect of 4 week supplementation with high dose ascorbic acid (AA) on levels of Pb in chicken blood, eggs and tissues. Ten clinically normal mixed-breed adult laying chickens were used. Chickens received Pb acetate (200 mg/kg/day) for 1 week. A group of chicken received AA (500 mg/kg/day) for 4 weeks and another did not receive any treatment. Blood, eggs and tissues were collected and analyzed for Pb contents using a graphite furnace atomic absorption spectrophotometer. The baseline blood Pb level was 47.5 ± 38.0 µg/L and increased significantly (P < 0.001) to 2755 ± 576 µg/L after 1 week of Pb acetate treatment. AA reduced blood Pb levels significantly (P < 0.05). Similarly, AA reduced Pb levels in ovaries, liver, eggshell, albumen, and yolk by 3, 2, 2.8, 6.8, and 2.2-fold, respectively. AA reduced concurrent elevated Pb levels in chicken tissues and eggs. Supplementing feed with high daily dose of AA might protect from Pb exposure when chickens are exposed to environmental Pb pollution.