4-Hydroxyquinolin-2-ones and their Close Structural Analogues as a New Source of Highly Effective Pain- Killers

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Publisher: 
InTech, Editors: Edited by Gabor B. Racz and Carl E. Noe
Description: 

Despite the most unflattering epithets and fear, pain was and still remains the normal response of any living organism on strong physical, chemical or mechanical stimuli. It has the most important protection function in nature – at just the right time pain immediately signals about appearance of exogenic or endogenic destructive effects on a certain organ [1-6], and it is simply necessary for the organism’s survival as a biological unit. Unfortunately, it presents not only by disagreeable sensation. Being rather complex psychophysiological phenomenon pain (especially strong and continued) is often accompanied by very powerful emotional stresses [7-9], which can rapidly exhaust the body’s adaptation resources and cause the serious disorders of its vital functions. Obviously it is for this reason that International Association for the Study of Pain considers pain as a global factor causing problems in modern society not only of medical, but also of socio-economic character