4-HYDROXY-2-QUINOLONES. 92*. REACTION OF 1-R-4-CHLORO-3-ETHOXYCARBONYL-2-OXO- 1,2- DIHYDROQUINOLINES WITH ANILINES

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Journal Title, Volume, Page: 
Chemistry of Heterocyclic Compounds, Vol. 42, No. 3, 2006
Year of Publication: 
2006
Authors: 
V. Ukrainets
L. V. Sidorenko
O. V. Gorokhova
N. A. Jaradat
Preferred Abstract (Original): 
A preparative method is proposed and the synthesis of 4-arylamino-2-oxo-1,2-dihydroquinolines has been effected. An X-ray structural investigation of 4-(4-chlorophenylamino)-2-oxo-1-propyl-1,2- dihydroquinoline-3-carboxylic acid has been carried out enabling the ease of decarboxylating such compounds to be substantiated. Results are given of a study of the anti-inflammatory activity of the synthesized compounds.
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