Variability of chemical compositions, antimicrobial and antioxidant activities of Ruta chalepensis leaf essential oils from three Palestinian regions.

Journal Title, Volume, Page:

BioMed Research International,

Year of Publication:

2017

Authors:

Nidal Jaradat

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box 7, Nablus, State of Palestine

Lina Adwan

College of Pharmacy, Nursing and Health Professions, Birzeit University, P.O. Box 14, Birzeit, State of Palestine

Shadi K’aibni

Center of Birzeit University Testing Laboratories, Birzeit University, P.O. Box 14, Birzeit, State of Palestine

Abdel Naser Zaid

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box 7, Nablus, State of Palestine

Munqez JY Shtaya

Department of Plant Production and Protection, Faculty of Agriculture and Veterinary Medicine

Naser Shraim

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box 7, Nablus, State of Palestine

Mohyeddin Assali

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box 7, Nablus, State of Palestine

Preferred Abstract (Original):

Interest in essential oils was recently revived with their popularity increasing in medicine, pharmacy, and

aromatherapy. This study was performed to identify the chemical compositions of the essential oil of Ruta chalepensis growing

wildly in three regions in Palestine and to assess and compare their antimicrobial and antioxidant activities. Methods. Identification

of the essential oil was performed by gas chromatography coupled with mass spectrometry (GC-MS). Antimicrobial activity was

tested against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Methicillin-Resistant Staphylococcus aureus, and

Candida albicans by using minimum inhibitory concentration (MIC) assay, while antioxidant activity was analyzed by using the

2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method. Results.The essential oils of R. chalepensis from Jerusalem

and Hebron regions have almost identical components; the major compounds identified were linalyl acetate and

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An-Najah Staff