Research Abstract:
Nowadays,
nanotechnology is gaining great concerns in many fields related to human
health and environment protection. One of these fields of most concern
is the control of the bacterial infection in a manner friendly to human
and the environment without forcing the bacterial population to emerge
as multidrug resistant strains. In this study, size selective synthesis
of ZnO and CoO nanoparticles is being prepared electrochemically and by
reduction method. Stabilization was achieved with alkyl quaternary
ammonium compound surfactants. From biological point of view, clinical
isolates of Staphylococcus aureus, Bacillus subtlis and Escherichia coli
were used for testing the antibacterial activity of the metallic oxide
nanoparticles and the stabilized forms in the surfactants. Antibacterial
activity of the surfactants, metallic oxide nanoparticles and the
surfactants stabilized metallic oxide nanoparticles were compared from
minimum in hibitory concentration (MBC) and minimum bactericidal
concentration (MIC). Dose response curves were applied when applicable
to support the data of MIC and MBC concentration. The surfactant, the
metallic oxide nanoparticles and the surfactant stabilized metallic
oxide nanoparticles showed a comparable antibacterial activity that
could reflects each material characteristics in comparison to the
bacterial strains bio- logical characteristics.