Management of Bladder Transitional Cell Carcinoma In Stage T1G3

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Journal Title, Volume, Page: 
Turkish Journal of Urology 2010;36(2):119-124
Year of Publication: 
Mahmoud Mustafa
Osmaniye State Hospital, Urology Department, Osmaniye, Turkey
Current Affiliation: 
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Tamer S. Barakat
Mansoura University, Urology and Nephrology Center, Mansoura, Egypt
Bedier Ali-El-Edein
Mansoura University, Urology and Nephrology Center, Mansoura, Egypt
Preferred Abstract (Original): 
Urothelial cancer staged as T1G3 presents urologist with challenges, because it has poor outcome if treated as superficial bladder tumor. Transurethral resection is the standard treatment for the non-muscle-invasive bladder tumor. However, high-grade T1 bladder tumor has potentially bad prognosis and transurethral resection is not adequate treatment option. The recurrence rate after transurethral resection is 50-80% and progression rate to muscle-invasive disease is 27-63%. The treatment of choice for patients with high grade T1 bladder tumor is a matter of controversy. Herein, we reviewed the literature and guidelines regarding the management of patients diagnosed with high-grade T1 urothelial cancer.
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