Two medicinal plants Rosmarinus officinalis and Salvia Fruticosa are
used in traditional medicine in Palestine for the treatment of
gastrointestinal tract, also as antiseptic, antispasmodic and wound
healing. In previous studies we have demonstrated the inhibitory effect
of different aqueous and organic extracts of the arial parts of these
shrubs. In this study we have been able to isolate the main active
ingredient of R. officinalis, which is called Verbenone. The isolated
compound was identified by means of different techniques such as UV. GC,
IR, HNMR and C 13 NMR, with respect to Salvia Fruticosa (triloba) grows
widely on the hills of the West Bank, and has been used by the local
population to relief intestinal pain . Intensive studies were conducted
to determine the organic and aqueous extracts of Salvia Fruticosa on
intestinal motility. In the current study, the aerial parts of Salvia
Fruticosa were collected and identified and the powdered were extracted
with n- Hexane , DCM and methanol. The n- Hexane crude extract was found
to be the most active with anti-inflammatory activity by inhibiting 5-
lipooxygenase and cyclooxygenase enzymes. The n- Hexane crude extract
was subjected to VLC and the fractions were collected and identified by
TLC, HPLC, GC- MS, HNMR and 13 C- NMR.
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