High Incidence of Penicillin Resistance amongst Clinical Isolates of Streptococcus Pneumoniae in Northern Palestine

Journal Title, Volume, Page:

J Med Microbiol December 1999 vol. 48 no. 12 1107-1110

Year of Publication:

1999

Link:

http://jmm.sgmjournals.org/content/48/12/1107.abstract

Authors:

K. ADWAN

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

Current Affiliation:

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

[email protected]

N. ABU-HASAN

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

A. HAMDAN

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

S. AL-KHALILI

Department of Biology and Biotechnology, Faculty of Science, An-Najah National University, Nablus, Palestine

Preferred Abstract (Original):

One hundred and thirteen consecutive isolates of Streptococcus pneumoniae were collected in Nablus, Palestine between March and Aug. 1997 from children with acute lower respiratory tract infections. Resistance rates were: penicillin 88%, cefuroxime 85%, erythromycin 63%, tetracycline 45%, chloramphenicol 27% and ofloxacin 2%. Resistances to erythromycin and cefuroxime were significantly associated with penicillin resistance. Ofloxacin may be useful against pneumococci resistant to traditional antimicrobial agents. Factors associated with penicillin resistance included hospitalisation and previous use of β-lactam antibiotics.

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High Incidence of Penicillin Resistance amongst Clinical Isolates of Streptococcus Pneumoniae in Northern Palestine