Pyridazine Nucleus: A Pharmacophoric Moiety For Bio-Active Compounds

2384's picture
Journal Title, Volume, Page: 
Aphcao 66,S35-S38.
Year of Publication: 
Naser, A.-Z.
Current Affiliation: 
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Baraldi, P. G.
Cacciari, B.
Pineda de Las Infantas, M. J.
Preferred Abstract (Original): 

The authors describe the substitution of an arom. ring with the pyridazine nucleus in the prepn. of several classes of bio-active compds. The authors described the prepn. of cardiotonics, of DNA minor groove binders such as tallimustine and anthramycin pyridazine analogs, and C-glycosides of pyridazines as antiviral agents.