The Synthesis of Novel Polycyclic Heterocyclic Ring Systems Via Photocyclization. 14. 14-Methylbenzo[h]naphtho-[1′2′:4,5]thieno[2,3-c][1,6]Naphthyridine

2187's picture
Journal Title, Volume, Page: 
Journal of Heterocyclic Chemistry Volume 31, Issue 2, pages 553–555, March/April 1994
Year of Publication: 
M. J. Musmar
Department of Chemistry, University of South Florida, Tampa, Florida 33620–5250 USA
Current Affiliation: 
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine
Raymond N. Castle
Department of Chemistry, University of South Florida, Tampa, FL 33620–5250 USA
Preferred Abstract (Original): 

Benzo[h]naphtho[1′2′:4,5]thieno[2,3-c][1,6]naphthyridine, a novel polycyclic heterocyclic ring system, has been synthesized as the 14-methyl derivative 8 in four steps from known intermediates. The structure of 8 is supported by assignment of the proton and the protonated carbon atoms by 2D-nmr techniques (COSY and a carbon-hydrogen one-bond coupling experiment).

The_Synthesis_of_Novel_Polycyclic_Heterocyclic_Ring_Systems_Via_Photocyclization._14._14-Methylbenzo[h]naphtho-[1′2′4,5]thieno[2,3-c][1,6]Naphthyridine.pdf683.12 KB