Research Abstract:
10-Ethyl-1-fluoro-lOH-[1]benzothieno[3',2':4,5]pyrido[2,3-c]carbazole,
10-ethyl-IOHJ1]benzothieno[3',2';4,5]pyrido[2,3-c]carbazole, and
12-ethyl-12H-naphtho[1",2";4',5']thieno[3',2':4,5]pyrido[2,3-c]carbazole
were prepared. Starting with the corresponding acid chlorides, namely,
4-flouro-3-chlorobenzo[b]thiophene-2-carbonyl chloride,
3-chlorobenzo[b]thiophene-2-carbonyl chloride, and
1-chloronaphtho[2,1-b]thiophene-2-carbonyl chloride, each carbonyl
chloride was then allowed to react with 3-amino-9-ethylcarbazole. The
carboxamides thus formed were converted to the corresponding lactams by
irradiation with a 450 watt Hanovia medium pressure mercury lamp under a
slow stream of air. The lactams were then chlorinated by refluxing in
phosphorus oxychoride. The carbazoles were then stirred with 10% Pd/C
under a hydrogen atmosphere to effect dechlorination to provide the
N-ethy1 derivatives.