Polarographic assay of Ranitidine Drugs in Pharmaceutical Formulations

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Journal Title, Volume, Page: 
Analytical Letters, Volume 21, Issue 10 October 1988 , pages 1845 - 1853
Year of Publication: 
Mohammed A. A. Hannoun
Current Affiliation: 
Department of Chemistry, Faculty of Science, An-Najah National University, Nablus, Palestine
Preferred Abstract (Original): 
A simple, accurate and rapid method for the quantitative determination of five ranitidine drugs in pharmaceutical formulations (Tablets and Ampoules) is proposed. The supporting electrolyte was acetic acid-sodium acetate buffer solution (pH 5.2). An excellent linear relationship was obtained between the concentration and current with correlation coefficient 0.9996. Good agreement was obtained between the results with the d.c. polarograhic method and those by the manufacturer's method of assay.